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Read instructions carefully before using Retin-A. Apply a thin layer of Retin-A to affected area at bedtime and wash hands immediately after applying. Avoid applying near the eyes, mouth, or open cuts because it can irritate sensitive skin. At first it might seem as though acne may appear to be worse, however, continue therapy. Sometimes it takes three to six weeks before the full benefits of this medication are seen. Using this medication more frequently or in excessive amounts does not improve the results, but may increase side effects.

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